THIS RESEARCH HAS BEEN APPROVED BY THE ANIMAL USE AND CARE (AUCC) COMMITTEE OF THE UNIVERSITY OF PRETORIA.

THIS RESEARCH IS FUNDED BY THE FACULTY OF VETERINARY SCIENCE, DEPARTMENT OF COMPANION ANIMAL CLINICAL STUDIES & THE ONDERSTEPOORT VETERINARY ACADEMIC HOSPITAL (OVAH) OF THE UNIVERSITY OF PRETORIA.

**Anonymity of patient information will be maintained in the interest of owners.

If you are interested or have any further queries, kindly contact:

1) Dr CK Lim (cheekin.lim@up.ac.za)

Tel: 012-529 8108, 072-708 4754, 076-9090 918

2) Prof Robert M Kirberger (Robert.kirberger@up.ac.za)

References

1. Olsen LH, Häggström J, Pedersen HD 2010 Acquired valvular heart disease. In: Ettinger,SJ, Feldman,EC (eds) Textbook of Veterinary Internal Medicine (Diseases of the dog and the cat) 7th ed., Vol 2, WB Saunders Co., Philadelphia, p1299-1319

2. Pedersen HD, Kristensen BO, Norby B, Lorentzen KA 1996 Echocardiographic study of mitral valve prolapse in dachshunds. Journal of Veterinary Medicine Series A 43:103-110

3. Pedersen HD, Olsen LH, Mow T, Christensen NJ 1999 Neuroendocrine changes in dachshunds with mitral valve prolapse examined under different study conditions. Research in Veterinary Science 66:11-17

4. Olsen LH, Fredholm M, Pedersen HD 1999 Epidemiology and inheritance of mitral valve prolapse in dachshunds. Journal of Veterinary Internal Medicine 13:448-456

5. Olsen LH, Martinussen T, Pedersen HD 2003 Early echocardiographic predictors of myxomatous mitral valve disease in dachshunds. Veterinary Record 152:293-297

6. Serfass P, Chetboul V, Sampedrano CC, Nicolle A, Benalloul T, Laforge H et al 2006 Retrospective study of 942 small-sized dogs: Prevalence of left apical systolic heart murmur and left-sided heart failure, critical effects of breed and sex. Journal of Veterinary Cardiology 8:11-18

7. Häggström J, Höglund K and Borgarelli M 2009 An update on treatment and prognostic indicators in canine myxomatous mitral valve disease. Journal of Small Animal Practice 50 : 25-33

8. Borgarelli M and Häggström J 2010 Canine degenerative myxomatous mitral valve disease: natural history, clinical presentation and therapy. Veterinary Clinics of North American Small Animal Practice 40: 651-63

9. Orton EC 2004 Mitral Valve Surgery: Current Veterinary Practice. 1st International Canine Valvular Disease Symposium Paris, October 30-31, 2004. Available from VIN Associate

10. Orton EC, Hackett TB, Mama K and Boon JA 2005 Technique and outcome of mitral valve replacement in dogs. Journal of the American Veterinary Medical Association 226: 1508-1511